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pentobarbital will lower the extent or outcome of cinacalcet by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.pentobarbital will increase toxicity of ifosfamide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. CYP3A4 inducers may perhaps improve the metabolism of ifosfamide to its Energetic a